Hi @sarah_swiss,
how do you separate the two (or more) target groups. I was thinking about using tags. So depending on the tag you move them through a kind of decision tree and build the separate mails (I am thinking of a drip campaign here) below the separate branches. Something like this:
You could do the split with the decisions after the first email (Email 1 in my example) theoretically, but I had this idea only after building the example.
But I am not sure, if this is what you would want to do.